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The Mprize, introduced in 2003, is designed to directly accelerate the development of revolutionary new life extension therapies. The prize pot continues to grow through donations; awards are made whenever a research team extends the life of mice. There are two categories of cash prizes:

  • Longevity - to the research team that breaks the world record for the oldest-ever mouse
  • Rejuvenation - to the team that develops the most successful late-onset rejuvenation that extends the life of the mice
 

The prize makes it possible to attract notable scientists from major universities like Dr. Andrzej Bartke, Southern Illinois University, who headed the team that holds the prize for longevity and Dr. Stephen Spindler, University of California, the prize holder for rejuvenation. In 2009 the first Special Mprize Lifespan Achievement Award went to Dr. Z. Dave Sharp for the successful healthy life extension of already aged mice using a pharmaceutical, rapamycin.

Meet the Competitors

Competition Rules and Application

Scientific Advisory Board: Meet the prestigious scientists who share our vision and enhance our ability to change the future of aging.

The Mprize springs from a simple truth: the greatest innovations in human history have always been fueled by three things ... competition, imagination, and the entrepreneurial spirit. The Mprize is a breakthrough approach that gives visionary competitors the resources they need to solve one of the largest humanitarian crises of our time. Meet the brilliant minds who are redefining the way we view aging.

 

Competitor Christian Sell

A decline in tissue function and protein synthesis occurs with increasing age. This catabolic state is associated with a decrease in the serum levels of IGF-I and IGF-I supplementation has been proposed as a therapy for elderly individuals. Not only is there a decline in the levels of IGF-I in the serum but the response of cells to IGF-I decreases with increasing age.

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